Reversion to susceptibility in a linezolid-resistant clinical isolate of Staphylococcus aureus
نویسندگان
چکیده
منابع مشابه
Susceptibility profile of methicillin-resistant Staphylococcus aureus to linezolid in clinical isolates
OBJECTIVE To determine the resistance and sensitivity pattern of methicillin-resistant Staphylococcus aureus (MRSA) isolates to linezolid (LZD) along with its prevalence in a tertiary care hospital of Karachi, Pakistan. MATERIALS AND METHODS A cross-sectional study was carried out. This study lasted for about 1 year. Prevalence and sensitivity of LZD, vancomycin, and oxacillin was tested agai...
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OBJECTIVES We report the case of a kidney-transplant patient, suffering an intra-abdominal abscess at the surgical site caused by a carbapenem-resistant ST258 Klebsiella pneumoniae clone, producing the KPC-3 carbapenemase. Under tigecycline treatment, the patient developed a sepsis caused by a carbapenem-susceptible ST258 K. pneumoniae strain. Complete DNA sequences of the plasmids carried by t...
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The emergence of a clinically daptomycin-resistant Staphylococcus aureus isolate occurred during treatment of methicillin-resistant S. aureus bacteremia and probable vertebral osteomyelitis. The breakthrough isolate was indistinguishable from pretreatment daptomycin-susceptible isolates by pulsed-field gel electrophoresis. Daptomycin nonsusceptibility was confirmed by MIC and time-kill curve an...
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متن کاملMethicillin-resistant Staphylococcus aureus with the MIC of linezolid
35 Methicillin-resistant Staphylococcus aureus with the MIC of linezolid 4 μg/ml, isolated from an 36 unsuccessful linezolid therapy patient, yielded linezolid-resistant mutants in blood agar at 48 h of 37 incubation. The resistant clones showed a MIC of linezolid ranging from 8 to 64 μg/ml and 38 accumulated the T2500A mutation(s) of the ribosomal RNA genes. Emergence of these resistant clones...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2004
ISSN: 1460-2091,0305-7453
DOI: 10.1093/jac/dkh423